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tgf-beta phospho-antibody microarray slides  (Full Moon BioSystems)

 
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    Full Moon BioSystems tgf-beta phospho-antibody microarray slides
    Activin receptor signaling regulates oligodendrocyte differentiation. a Mean number of oligodendrocyte lineage cells (Olig2+) per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). b Mean proportion of oligodendrocyte lineage cells (Olig2+) which are mature oligodendrocytes (CC1+) versus immature cells (CC1−), per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Multiple t tests with false discovery rate of 1%, *** P = 0.000026. c Images of differentiating oligodendrocytes (cytoplasmic Olig1+ and nuclear Olig2+) in corpus callosum of P16 Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. d Mean number of cytoplasmic Olig1 and Olig2 double positive cells per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Two-tailed Student’s t test, ** P = 0.0047, 0.0026, respectively. e Images of maturing oligodendrocytes (MAG+ MBP−) at P1 in corpus callosum of Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. f Mean number of MAG+ cultured oligodendrocytes per field in vehicle control-treated or activin-A-treated conditions (10 ng ml −1 ) in vitro. n = 3 biological replicates. Two-tailed paired Student’s t test, * P = 0.0484. g Images of cultured OPCs treated with vehicle or 10 ng ml −1 activin-A and immunostained for MAG (green), counterstained with Hoechst (blue). Scale bar 25 μm. h Data-mining of <t>microarray</t> of human fetal brain at 9 and 12 gestational weeks (gw) represented as fold change in expression (normalized to 9 gw), showing paralleled expression changes between activin-A ( INHBA ) and oligodendrocyte differentiation-associated genes ( MAG , MOG ) in development
    Tgf Beta Phospho Antibody Microarray Slides, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tgf-beta phospho-antibody microarray slides/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    tgf-beta phospho-antibody microarray slides - by Bioz Stars, 2026-05
    90/100 stars

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    1) Product Images from "Activin receptors regulate the oligodendrocyte lineage in health and disease"

    Article Title: Activin receptors regulate the oligodendrocyte lineage in health and disease

    Journal: Acta Neuropathologica

    doi: 10.1007/s00401-018-1813-3

    Activin receptor signaling regulates oligodendrocyte differentiation. a Mean number of oligodendrocyte lineage cells (Olig2+) per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). b Mean proportion of oligodendrocyte lineage cells (Olig2+) which are mature oligodendrocytes (CC1+) versus immature cells (CC1−), per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Multiple t tests with false discovery rate of 1%, *** P = 0.000026. c Images of differentiating oligodendrocytes (cytoplasmic Olig1+ and nuclear Olig2+) in corpus callosum of P16 Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. d Mean number of cytoplasmic Olig1 and Olig2 double positive cells per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Two-tailed Student’s t test, ** P = 0.0047, 0.0026, respectively. e Images of maturing oligodendrocytes (MAG+ MBP−) at P1 in corpus callosum of Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. f Mean number of MAG+ cultured oligodendrocytes per field in vehicle control-treated or activin-A-treated conditions (10 ng ml −1 ) in vitro. n = 3 biological replicates. Two-tailed paired Student’s t test, * P = 0.0484. g Images of cultured OPCs treated with vehicle or 10 ng ml −1 activin-A and immunostained for MAG (green), counterstained with Hoechst (blue). Scale bar 25 μm. h Data-mining of microarray of human fetal brain at 9 and 12 gestational weeks (gw) represented as fold change in expression (normalized to 9 gw), showing paralleled expression changes between activin-A ( INHBA ) and oligodendrocyte differentiation-associated genes ( MAG , MOG ) in development
    Figure Legend Snippet: Activin receptor signaling regulates oligodendrocyte differentiation. a Mean number of oligodendrocyte lineage cells (Olig2+) per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). b Mean proportion of oligodendrocyte lineage cells (Olig2+) which are mature oligodendrocytes (CC1+) versus immature cells (CC1−), per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Multiple t tests with false discovery rate of 1%, *** P = 0.000026. c Images of differentiating oligodendrocytes (cytoplasmic Olig1+ and nuclear Olig2+) in corpus callosum of P16 Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. d Mean number of cytoplasmic Olig1 and Olig2 double positive cells per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Two-tailed Student’s t test, ** P = 0.0047, 0.0026, respectively. e Images of maturing oligodendrocytes (MAG+ MBP−) at P1 in corpus callosum of Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. f Mean number of MAG+ cultured oligodendrocytes per field in vehicle control-treated or activin-A-treated conditions (10 ng ml −1 ) in vitro. n = 3 biological replicates. Two-tailed paired Student’s t test, * P = 0.0484. g Images of cultured OPCs treated with vehicle or 10 ng ml −1 activin-A and immunostained for MAG (green), counterstained with Hoechst (blue). Scale bar 25 μm. h Data-mining of microarray of human fetal brain at 9 and 12 gestational weeks (gw) represented as fold change in expression (normalized to 9 gw), showing paralleled expression changes between activin-A ( INHBA ) and oligodendrocyte differentiation-associated genes ( MAG , MOG ) in development

    Techniques Used: Two Tailed Test, Cell Culture, Control, In Vitro, Microarray, Expressing



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    tgf-beta phospho-antibody microarray slides  (Full Moon BioSystems)
    90
    Full Moon BioSystems tgf-beta phospho-antibody microarray slides
    Activin receptor signaling regulates oligodendrocyte differentiation. a Mean number of oligodendrocyte lineage cells (Olig2+) per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). b Mean proportion of oligodendrocyte lineage cells (Olig2+) which are mature oligodendrocytes (CC1+) versus immature cells (CC1−), per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Multiple t tests with false discovery rate of 1%, *** P = 0.000026. c Images of differentiating oligodendrocytes (cytoplasmic Olig1+ and nuclear Olig2+) in corpus callosum of P16 Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. d Mean number of cytoplasmic Olig1 and Olig2 double positive cells per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Two-tailed Student’s t test, ** P = 0.0047, 0.0026, respectively. e Images of maturing oligodendrocytes (MAG+ MBP−) at P1 in corpus callosum of Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. f Mean number of MAG+ cultured oligodendrocytes per field in vehicle control-treated or activin-A-treated conditions (10 ng ml −1 ) in vitro. n = 3 biological replicates. Two-tailed paired Student’s t test, * P = 0.0484. g Images of cultured OPCs treated with vehicle or 10 ng ml −1 activin-A and immunostained for MAG (green), counterstained with Hoechst (blue). Scale bar 25 μm. h Data-mining of <t>microarray</t> of human fetal brain at 9 and 12 gestational weeks (gw) represented as fold change in expression (normalized to 9 gw), showing paralleled expression changes between activin-A ( INHBA ) and oligodendrocyte differentiation-associated genes ( MAG , MOG ) in development
    Tgf Beta Phospho Antibody Microarray Slides, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tgf-beta phospho-antibody microarray slides/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    tgf-beta phospho-antibody microarray slides - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Activin receptor signaling regulates oligodendrocyte differentiation. a Mean number of oligodendrocyte lineage cells (Olig2+) per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). b Mean proportion of oligodendrocyte lineage cells (Olig2+) which are mature oligodendrocytes (CC1+) versus immature cells (CC1−), per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Multiple t tests with false discovery rate of 1%, *** P = 0.000026. c Images of differentiating oligodendrocytes (cytoplasmic Olig1+ and nuclear Olig2+) in corpus callosum of P16 Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. d Mean number of cytoplasmic Olig1 and Olig2 double positive cells per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Two-tailed Student’s t test, ** P = 0.0047, 0.0026, respectively. e Images of maturing oligodendrocytes (MAG+ MBP−) at P1 in corpus callosum of Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. f Mean number of MAG+ cultured oligodendrocytes per field in vehicle control-treated or activin-A-treated conditions (10 ng ml −1 ) in vitro. n = 3 biological replicates. Two-tailed paired Student’s t test, * P = 0.0484. g Images of cultured OPCs treated with vehicle or 10 ng ml −1 activin-A and immunostained for MAG (green), counterstained with Hoechst (blue). Scale bar 25 μm. h Data-mining of microarray of human fetal brain at 9 and 12 gestational weeks (gw) represented as fold change in expression (normalized to 9 gw), showing paralleled expression changes between activin-A ( INHBA ) and oligodendrocyte differentiation-associated genes ( MAG , MOG ) in development

    Journal: Acta Neuropathologica

    Article Title: Activin receptors regulate the oligodendrocyte lineage in health and disease

    doi: 10.1007/s00401-018-1813-3

    Figure Lengend Snippet: Activin receptor signaling regulates oligodendrocyte differentiation. a Mean number of oligodendrocyte lineage cells (Olig2+) per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). b Mean proportion of oligodendrocyte lineage cells (Olig2+) which are mature oligodendrocytes (CC1+) versus immature cells (CC1−), per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Multiple t tests with false discovery rate of 1%, *** P = 0.000026. c Images of differentiating oligodendrocytes (cytoplasmic Olig1+ and nuclear Olig2+) in corpus callosum of P16 Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. d Mean number of cytoplasmic Olig1 and Olig2 double positive cells per field ± s.e.m. in corpus callosum of P16 Acvr1b fl/fl ( n = 3 mice), PDGFRa-Cre; Acvr1b fl/+ ( n = 4 mice) and PDGFRa-Cre; Acvr1b fl/fl mice ( n = 7 mice). Two-tailed Student’s t test, ** P = 0.0047, 0.0026, respectively. e Images of maturing oligodendrocytes (MAG+ MBP−) at P1 in corpus callosum of Acvr1b fl/fl and PDGFRa-Cre; Acvr1b fl/fl mice. Scale bar 25 μm. f Mean number of MAG+ cultured oligodendrocytes per field in vehicle control-treated or activin-A-treated conditions (10 ng ml −1 ) in vitro. n = 3 biological replicates. Two-tailed paired Student’s t test, * P = 0.0484. g Images of cultured OPCs treated with vehicle or 10 ng ml −1 activin-A and immunostained for MAG (green), counterstained with Hoechst (blue). Scale bar 25 μm. h Data-mining of microarray of human fetal brain at 9 and 12 gestational weeks (gw) represented as fold change in expression (normalized to 9 gw), showing paralleled expression changes between activin-A ( INHBA ) and oligodendrocyte differentiation-associated genes ( MAG , MOG ) in development

    Article Snippet: Samples were applied to TGF-β phospho-antibody microarray slides (Full Moon Biosystems) which have 176 immobilized antibodies against phosphorylated and unphosphorylated specific residues in proteins associated with the 5 TGFβ signaling pathways, with 6 technical replicates per antibody.

    Techniques: Two Tailed Test, Cell Culture, Control, In Vitro, Microarray, Expressing